Achieving sustainability targets over the long term will mean that individuals, companies, organizations and industries need to both measure and manage various aspects of sustainability. While greenhouse gas emissions may remain at the forefront, other environmental, social and economic factors also need to be regarded. The role of handprint is also emerging as a key factor that can accelerate the transition towards a more sustainable world. As various organizations move towards sustainability targets, the efforts needed will become more specific and could possibly involve more holistic and ambitious transformation of operations. How this can be done while minimizing disruption and maximizing opportunity to various societal stakeholders remains a fundamental challenge that requires increasing efforts to find sustainable solutions. More specific goals and targets will need to be defined by new or more accurate indicators. Achieving 90% of almost any goal is often easy. The last 10% may require more intense or even radical actions that can only be achieved through societal renovation.